研究方向
基因调控网络的结构,动力学性质及进化。 衰老的分子生物学机制
代表性科研论文
1. H. Li, R. Helling, C. Tang & N. Wingreen. Emergence of preferred structures in a simple model of protein folding. Science 273, 666 (1996).
2. H. Bussemaker, H. Li & E. Siggia. Building a dictionary for genomes: Identification of presumptive regulatory sites by statistical analysis. Proc. Natl. Acad. Sci. USA 97, 10096 (2000).
3. S. A. McCarroll, C. T. Murphy, S. Zou, S. D. Pletcher, C. S. Chin, Y. N. Jan, C. Kenyon, C. I. Bargmann, and H. Li . Comparing genomic expression patterns across species identifies shared transcriptional program in aging, Nature Genetics 36, 197 (2004).
4. B. Tuch, D. Galgoczy, A. Hernday, H. Li, and A. D. Johnson, The evolution of combinatorial gene regulation in fungi, PLoS Biology 2008 6(2):e38
5. C. Chin, V. Chubukov, E. Jolly, J. DeRisi, H. Li (2008), Dynamics and design principles of a basic regulatory architecture controlling metabolic pathways, PLoS Biology 6(6): e146