研究方向：
1. 离子通道电生理学
2. 钙信号转导相关蛋白的冷冻电镜结构生物学
3. 细胞钙信号（钙火花、钙火星）的时空动态和分子机制
4. 细胞钙稳态机制和钙信号转导调控
5. 细胞钙紊乱及心脏疾病的分子机制和早期干预
6.冬眠动物细胞稳态和代谢调控及冬眠诱导
代表性科研论文：
1. Yang L, Li RC, Xiang B, Li YC, Wang LP, et al, Wang SQ* (2021) Transcriptional regulation of intermolecular Ca2+ signaling in ground squirrel cardiomyocytes: the myocardin- junctophilin axis. Proc. Natl. Acad. Sci. U.S.A. 2021;118:/e2025333118.
2. Li LL, Guo QJ, et al, Cui BX*, Wang SQ* (2020) Nanobar array assay revealed complementary roles of bin1 splice isoforms in cardiac T-tubule morphogenesis. Nano Letters, 20(9):6387-6395.【封面论文】
3. Yang HQ, Zhou P, Wang LP, et al, Wang SQ* (2020) Compartmentalized β1-adrenergic signaling synchronizes excitation-contraction coupling without modulating individual Ca2+ sparks in healthy and hypertrophied cardiomyocytes. Cardiov. Res., 116:2069-2080.【述评：Cardiov. Res. 116:2033–2035】
4. Yang HQ, Wang LP, Gong Y, et al, Wang SQ* (2019) β2-Adrenergic stimulation compartmentalizes β1 signaling into nanoscale local domains by targeting the C-terminus of β1-adrenoceptors. Circ. Res., 124:1350-1359.【亮点、封面论文】
5. Zhao YT, Guo YB, et al, Wang SQ (2017) Sensitized signaling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes. Cardiov. Res. 113:332-342.【述评：Cardiov. Res.113, 256–258】
6. Xiao E, Yang H, et al, Wang SQ*, Zhang Y* (2015) TRPM7 Senses mechanical stimulation inducing osteogenesis in human bone marrow mesenchymal stem cells. Stem Cells, 33:615-621.
7. Shang W, Lu F, et al, Wang SQ*, Cheng H* (2014) Imaging Ca2+ nanosparks in heart with a new targeted biosensor. Cir. Res. 114:412-420.【述评: Circ. Res.114:412-420】
8. Li RC, Tao J, Guo YB, Wu HD, et al, Xu M*, Wang SQ* (2013) In vivo suppression of microRNA-24 prevents the transition toward decompensated hypertrophy in aortic-constricted mice. Circ. Res. 112:601-605.
9. Zhang HB, Li RC, Xu M, et al, Wang SQ* (2013) Ultrastructural uncoupling between T-tubules and sarcoplasmic reticulum in human heart failure. Cardiov. Res. 98:269-276.【封面论文】
10. Xu M, Wu HD, Li RC, Zhang HB, et al, Wang XJ*, Meng X, and Wang SQ* (2012) MiR-24 regulates junctophilin-2 expression in cardiomyocytes. Circ. Res. 111:837-841.【述评: Circ. Res.111:816-818】
